N,N-dimethylaniline; production methods
Posted 05 July 2006 - 08:07 PM
Its synthesis uses aniline as a precursor, and almost any type of methylating agent. On orgsyn, a synthesis on the same basic principal (methylation of a primary amine) uses trimethyl phosphate as a methylating agent. AFAIK, trimethyl phosphate can be produced by esterication of methanol with phosphoric acid. I found no information to prove otherwise.
A text document I recently found gave a synthesis that used paraformaldehyde and oxalic acid dihydrate (I will gladly post this doccument if anyone would like to see it).
The method that I thought might work would be aniline reacted with methyl iodide.
C6H5NH2 + 2CH3I ----> C6H5N(CH3)2 + 2HI
I first thought of methyl bromide since alkyl bromides are usually cheaper, but then I remembered that methyl bromide is a gas till 3C IIRC. Methyl Iodide however has a BP of 42C. After the reaction, the dimethylaniline could simply be distilled off. You would also get hydroiodic acid depending on the water in the solution, which could be used to make more methyl iodide. I will attempt this once I make some methyl iodide and post how it goes. Can anyone contribute their two cents to this? Or does anyone know of another synth?
Posted 05 July 2006 - 10:21 PM
My DMA is almost completly clear, not really yellow or brown at all, it depends on the purity. Also, DMA does not smell like hexamine or anything like that, it has distinctly aromatic smell. It smells almost exactly like naphthalene.
N,N-dimethylaniline is a yellow to brown liquid with an amine type odor (think hexamine or methylamine).
My PGP key fingerprint: 34EA E404 F18F B916 EBFC 21AB 865B A549 0818 985B
Posted 06 July 2006 - 09:59 AM
Posted 06 July 2006 - 09:00 PM
The top post shows a synthesis. Although that method was designed for ethyl iodide, methanol can be substituted with yeilds no less than 50% (which is a terrible yeild considering the price of iodine, but I'll see how it goes).
As for the DMS synth, what kind of yeild did you get, using what concentration sulfuric acid. Thats all I'm worried about. If you feel like posting the whole synth in a seperate thread in the chemistry section, I'm sure this board would benefit from it but I'm sure very few people will use it.
Posted 07 July 2006 - 12:37 AM
Posted 07 July 2006 - 05:51 AM
I read that as "... and a respirator, maybe two"
Yeah sure one for the cat as well.
Is it really that bad? I mean bad as in HCN, or just bad as in huffing CHCl3, or a one-liter runaway-nitration in your fridge?
I ordered NaI, should come next week. So yes please do post the results, even if it will be the ethyl version for me. Still going after EtNO2 you know? And later some N-methylation would be nice.
All for the cat of course...
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